西亚试剂：Ethylene Modulates Stem Cell Division in the Arabidopsis th

Ethylene Modulates Stem Cell Division in the Arabidopsis thaliana Root
Olga Ortega-Martínez,* Monica Pernas,* Rachel J. Carol, Liam Dolan

The construction of multicellular organisms depends on stem cells—cells that can both regenerate and produce daughter cells that undergo differentiation. Here, we show that the gaseous messenger ethylene modulates cell division in the cells of the quiescent center, which act as a source of stem cells in the seedling root. The cells formed through these ethylene-induced divisions express quiescent center-specific genes and can repress differentiation of surrounding initial cells, showing that quiescence is not required for these cells to signal to adjacent stem cells. We propose that ethylene is part of a signaling pathway that modulates cell division in the quiescent center in the stem cell niche during the postembryonic development of the root system.

Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, UK.

* These authors contributed equally to this work.

 Present address: Kristineberg Marine Research Station, Kristineberg 566, 450 34 Fiskebäckskil, Sweden.

 École Pratique des Hautes Études, 46 rue de Lille, 75007 Paris, France.

 To whom correspondence should be addressed. E-mail:

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