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Major Publications
1. Strasser A, Harris AW, Bath ML, Cory S.
Novel primitive lymphoid tumours induced in transgenic mice by cooperation
between myc and bcl-2. Nature. 1990 Nov 22;348(6299):331-3.
PMID: 2250704 [PubMed - indexed for MEDLINE]
2. Strasser A, Whittingham S, Vaux DL, Bath ML, Adams JM, Cory S, Harris AW.
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and
elicits autoimmune disease. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8661-5.
PMID: 1924327 [PubMed - indexed for MEDLINE]
3. Strasser A, Harris AW, Cory S.
bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell. 1991 Nov 29;67(5):889-99.
PMID: 1959134 [PubMed - indexed for MEDLINE]
4. Strasser A, Harris AW, Corcoran LM, Cory S.
Bcl-2 expression promotes B- but not T-lymphoid development in scid mice. Nature. 1994 Mar 31;368(6470):457-60.
PMID: 8133891 [PubMed - indexed for MEDLINE]
5. Strasser A, Harris AW, Jacks T, Cory S.
DNA damage can induce apoptosis in proliferating lymphoid cells via
p53-independent mechanisms inhibitable by Bcl-2. Cell. 1994 Oct 21;79(2):329-39.
PMID: 7954799 [PubMed - indexed for MEDLINE]
6. Strasser A, Harris AW, Huang DC, Krammer PH, Cory S.
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 1995 Dec 15;14(24):6136-47.
PMID: 8557033 [PubMed - indexed for MEDLINE]
7. Maraskovsky E, O'Reilly LA, Teepe M, Corcoran LM, Peschon JJ, Strasser A.
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient
mice but not in mutant rag-1-/- mice. Cell. 1997 Jun 27;89(7):1011-9.
PMID: 9215624 [PubMed - indexed for MEDLINE]
8. Newton K, Harris AW, Bath ML, Smith KG, Strasser A.
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive
thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 1998 Feb 2;17(3):706-18.
PMID: 9450996 [PubMed - indexed for MEDLINE]
9. Puthalakath H, Huang DC, O'Reilly LA, King SM, Strasser A.
The proapoptotic activity of the Bcl-2 family member Bim is regulated by
interaction with the dynein motor complex. Mol Cell. 1999 Mar;3(3):287-96.
PMID: 10198631 [PubMed - indexed for MEDLINE]
10. Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F, Adams JM, Strasser A.
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses,
leukocyte homeostasis, and to preclude autoimmunity. Science. 1999 Nov 26;286(5445):1735-8.
PMID: 10576740 [PubMed - indexed for MEDLINE]
11. Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A.
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V
actin motor complex, activated by anoikis. Science. 2001 Sep 7;293(5536):1829-32. Erratum in: Science 2002 Aug 16;297(5584):1122.
PMID: 11546872 [PubMed - indexed for MEDLINE]
12. Bouillet P, Purton JF, Godfrey DI, Zhang LC, Coultas L, Puthalakath H, Pellegrini M, Cory S, Adams JM, Strasser A.
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive
thymocytes. Nature. 2002 Feb 21;415(6874):922-6. Erratum in: Nature 2002 Jul 4;618(6893):108.
PMID: 11859372 [PubMed - indexed for MEDLINE]
13. Marsden VS, O'Connor L, O'Reilly LA, Silke J, Metcalf D, Ekert PG, Huang DC, Cecconi F, Kuida K, Tomaselli KJ, Roy S, Nicholson DW, Vaux DL, Bouillet P, Adams JM, Strasser A.
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the
cytochrome c/Apaf-1/caspase-9 apoptosome. Nature. 2002 Oct 10;419(6907):634-7. Epub 2002 Sep 25.
PMID: 12374983 [PubMed - indexed for MEDLINE]
14. Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, Adams JM, Strasser A.
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma
and noxa. Science. 2003 Nov 7;302(5647):1036-8. Epub 2003 Sep 18.
PMID: 14500851 [PubMed - indexed for MEDLINE]
15. Strasser A, O'Connor L, Dixit VM.
Apoptosis signaling. Annu Rev Biochem. 2000;69:217-45. Review.
PMID: 10966458 [PubMed - indexed for MEDLINE]