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Transformation of Different Human Breast Epithelial Cell Types Leads to Distinct Tumor Phenotypes
Tan A. Ince, Andrea L. Richardson, George W. Bell, Maki Saitoh, Samuel Godar, Antoine E. Karnoub, James D. Iglehart, and Robert A. Weinberg
[Summary] [Full Text] [PDF] [Supplemental Data]
作者简介:
Robert A. Weinberg, Ph.D.
Member, Whitehead Institute
Professor of Biology, MIT
SELECTED PUBLICATIONS
Orimo, A., Gupta, P.B., Sgroi, D.C., Arenzana-Seisdedos, F., Delaunay, T., Rizwan, N., Carey, V.J., Richardson, A.L., and Weinberg, R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell, 121: 335-348. (2005).
Ben-Porath, I. and Weinberg, R.A. When cells get stressed:an integrative view of cellular senescence. Journal of Clinical Investigation, 113(1):8-13. (2004).
Kuperwasser, C., Chavarria, T., Wu, M., Magrane, G., Gray, J.W., Carey, L., Richardson, A., and Weinberg, R.A. Recreation of functional normal and malignant human breast tissues in mice. PNAS, 101: 4966-4971. (2004).
Yang, J., Mani, S.A., Liu Donaher, J., Richardson, A., Ramaswamy, S., Gitelman, I., and Weinberg, R.A. Twist, a master regulator of morphogenesis plays an essential role in tumor metastasis. Cell, 117:927-939. (2004).
Rangarajan, A., Hong, S.J. Gifford, A., and Weinberg R. A. Species-and cell type-specific requirements for cellular transformation. Cancer Cell, 6:171-183. (2004).
Dessain, S.K., Adekar, S.P., Stevens, J.B., Carpenter, K.A., Skorski, M.L., Goldsby, R.A., and Weinberg, R.A. High efficiency creation of human monoclonal antibody-producing hybridomas. The Journal of Immunological Methods, 291:109-122. (2004).
Ben-Porath, I., and Weinberg, R.A. The signals and pathways activating cellular senescence. International Journal of Biochemistry and Cell Biology, 961-976. (2004).
Weinberg, R.A. Inadvertent Cancer Research. Cancer Biology & Therapy, 3:100-101. (2004).