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西亚试剂::Genome-wide association study dissects the genetic

Hui Li Zhiyu Peng Xiaohong Yang Weidong Wang Junjie Fu Jianhua Wang Yingjia HanYuchao Chai Tingting Guo Ning Yang Jie Liu Marilyn L Warburton Yanbing Cheng Xiaomin Hao Pan Zhang Jinyang Zhao Yunjun Liu Guoying Wang Jiansheng Li Jianbing Yan

Maize kernel oil is a valuable source of nutrition. Here we extensively examine the genetic architecture of maize oil biosynthesis in a genome-wide association study using 1.03 million SNPs characterized in 368 maize inbred lines, including 'high-oil' lines. We identified 74 loci significantly associated with kernel oil concentration and fatty acid composition (P < 1.8 × 10−6), which we subsequently examined using expression quantitative trait loci (QTL) mapping, linkage mapping and coexpression analysis. More than half of the identified loci localized in mapped QTL intervals, and one-third of the candidate genes were annotated as enzymes in the oil metabolic pathway. The 26 loci associated with oil concentration could explain up to 83% of the phenotypic variation using a simple additive model. Our results provide insights into the genetic basis of oil biosynthesis in maize kernels and may facilitate marker-based breeding for oil quantity and quality.

丙烯醛肉桂醛桂皮醛4-硝基肉桂醛