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西亚试剂:Dialogue between RhoA/ROCK and Members of the Par Complex i

Dialogue between RhoA/ROCK and Members of the Par Complex in Cell Polarity

Raffaella Sordella and Linda Van Aelst,

Summary

Cell polarity is essential for many biological processes and is regulated by conserved protein complexes, including the Par complex, Rho GTPases, and their regulators. In this issue of Developmental Cell, studies by Nakayama et al. and Zhang and Macara examine how interplay between Rho GTPases and the Par complex control polarized cell migration and dendritic spine morphogenesis in alternate ways.