西亚试剂：Caspase Activity Mediates the Differentiation of Embryonic

Caspase Activity Mediates the Differentiation of Embryonic Stem Cells
Jun Fujita,1,7 Ana M. Crane,1,7 Marlon K. Souza,1,7 Marion Dejosez,1 Michael Kyba,4 Richard A. Flavell,5 James A. Thomson,6 and Thomas P. Zwaka1,2,3,

1 Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA
2 Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA
3 Department of Molecular Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
4 Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
5 Department of Immunobiology, Yale University School of Medicine and Howard Hughes Medical Institute, New Haven, CT 06520, USA
6 The Wisconsin National Primate Research Center, University of Wisconsin, Madison, Madison, WI 53715, USA

Cell Stem Cell，Vol 2, 584-594, 05 June 2008，Viktor Janzen, David T. Scadden

Hematopoietic Stem Cell Responsiveness to Exogenous Signals Is Limited by Caspase-3
Viktor Janzen,1,2,3,7 Heather E. Fleming,1,2 Tamara Riedt,3 Göran Karlsson,4 Matthew J. Riese,1 Cristina Lo Celso,1,2 Griffin Reynolds,1 Craig D. Milne,5 Christopher J. Paige,5 Stefan Karlsson,4 Minna Woo,6 and David T. Scadden1,2,

1 Center for Regenerative Medicine, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
2 Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
3 Department of Internal Medicine II, Division for Hematology, Oncology, and Immunology, Eberhard-Karls-University Tübingen, 72076 Tübingen, Germany
4 Department of Molecular Medicine and Gene Therapy, Institute of Laboratory Medicine, Lund University Hospital and Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, SE-221 84 Lund, Sweden
5 Department of Immunology, University Health Network, Ontario Cancer Institute, University of Toronto, Toronto, Ontario M5G 2M9, Canada
6 Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto, Ontario M5G 2M9, Canada

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