西亚试剂：Dnmt3a silences hematopoietic stem cell self-renewal

Dnmt3a silences hematopoietic stem cell self-renewal

Jennifer J. Trowbridge & Stuart H. Orkin

DNA methylation is an epigenetic mark stably directing gene expression throughout development. A new study uncovers a role for the DNA methyltransferase Dnmt3a in silencing self-renewal genes in hematopoietic stem cells (HSCs) to permit efficient hematopoietic differentiation.

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