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Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis
Zhang Z, Lv X, Jiang J, Zhang L, Zhao Y.
Stem cell niche is a specialized microenvironment crucial for stem cell self-renewal. Drosophila testis contains two types of stem cells: germline stem cells (GSCs) and somatic cyst stem cells (CySCs), providing a good model for studying niche-stem cell interaction1..