西亚试剂：OSCA1 mediates osmotic-stress-evoked Ca2+increases vital fo

OSCA1 mediates osmotic-stress-evoked Ca2+increases vital for osmosensing in Arabidopsis

Fang Yuan, Huimin Yang, Yan Xue, Dongdong Kong, Rui Ye, Chijun Li, Jingyuan Zhang,Lynn Theprungsirikul, Tayler Shrift, Bryan Krichilsky, Douglas M. Johnson, Gary B. Swift,Yikun He, James N. Siedow & Zhen-Ming Pei

Water is crucial to plant growth and development. Environmental water deficiency triggers an osmotic stress signalling cascade, which induces short-term cellular responses to reduce water loss and long-term responses to remodel the transcriptional network and physiological and developmental processes1, 2, 3, 4. Several signalling components that have been identified by extensive genetic screens for altered sensitivities to osmotic stress seem to function downstream of the perception of osmotic stress. It is known that hyperosmolality and various other stimuli trigger increases in cytosolic free calcium concentration ([Ca2+]i)5, 6. Considering that in bacteria and animals osmosensing Ca2+ channels serve as osmosensors7, 8, hyperosmolality-induced [Ca2+]iincreases have been widely speculated to be involved in osmosensing in plants1, 9. However, the molecular nature of corresponding Ca2+ channels remain unclear6, 10, 11.（doi: 10.1038/nature13593）

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