异硫氰酸荧光素酯-西亚试剂

CAS号: 3326-32-7

英文名称: Fluorescein isothiocyanate isomer I

英文同义词: to-;FITC;FITC;FITC;FITC;5-FITC;FITC-I;FITC-I)F;FITC ISOMER;PLAUR）

中文名称: 异硫氰酸荧光素酯

中文同义词: 异硫氰酸荧光黄;异硫氰酸荧光红;异硫氰酸荧光橙红;异硫氰酸荧光素脂;荧光胺异硫腈酸盐;异硫氰酸荧光素酯;5-异氰硫基荧光素;荧光5-异硫氰酸酯;5-异硫氰酸荧光素;异硫氰酸荧光酯异构体

CBNumber: CB0173162

分子式: C21H11NO5S

分子量: 389.38

MOL File: 3326-32-7.mol

异硫氰酸荧光素酯化学性质

熔点 : >360 °C(lit.)

沸点 : 708.6±60.0 °C(Predicted)

密度 : 1.3423 (rough estimate)

折射率 : 1.5060 (estimate)

储存条件 : 2-8°C

溶解度 : Slightly soluble in DMSO, ethanol, methanol DMF and acetone

酸度系数(pKa): 2.2, 4.4, 6.7(at 25℃)

形态: powder

颜色: White

酸碱指示剂变色ph值范围: Weak green uorescence (6.0) to strong green uorescence (7.2)

水溶解性 : practically insoluble

最大波长(λmax): 490nm

敏感性 : Moisture Sensitive

BRN : 1407295

稳定性: Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.

主要应用: Magnetic nanowires, immunoassays, analyzing proteins, identifying chromosomes, Salmonella mosomes, diagnosis of cancer, kidney diseases, detecting pathogens, genes, Salmonella cells, toxoplasmosis, enzyme-mediated nucleic acid cleavage, surface molecules on colorectal cancers, treating cancer, chronic lymphocytic leukemia

生物领域应用: Analyzing sugar chain; detecting iodide/iodate or total iodine; detecting/imaging thiols; detecting/quantifying biotin derivatives;16 diagnosing classical Hodgkin lymphoma (CHL) in lymph nodes; cellulose nanocrystals for bioimaging applications; treating neuroinflammation; treating/diagnosing cancer; PEO-PCL-PEO triblock copolymers for topical delivery; polymersomes in biomedical or cosmetic applications;apoptosis assay; as a substrate for measuring heparanase activity, human immunodeficiency virus (HIV-1) proteinase activity, kinase activity, phosphatase activity, β-lactamase activity, transglutaminase (TG2) activity; implantable drug-delivery devicess

InChIKey: MHMNJMPURVTYEJ-UHFFFAOYSA-N

安全信息

危险品标志 : Xn,Xi

危险类别码 : 42/43-36/37/38-22

安全说明 : 22-45-36/37/39-26-36/37-36

WGK Germany : 3

F : 10

TSCA : Yes

海关编码 : 29329990

异硫氰酸荧光素酯性质、用途与生产工艺

用途

异硫氰酸荧光素酯能和各种抗体蛋白结合，结合后的抗体不丧失与一定抗原结合的特异性，并在碱性溶液中具有强烈的黄绿色荧光。通过在荧光显微镜下观察或流式细胞仪分析可对相应抗原进行定性、定位或定量的检测。用于医学，农学和畜牧等方面，可对由细菌病毒和寄生虫等所致疾病进行快速诊断。