化学性质
属性
溶解性
DMSO mg/mL
Water mg/mL
Ethanol mg/mL
存贮条件
储存温度-20°C
描述
别名
2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride;2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride
生化机理
GW791343 is a P2X7 allosteric modulator. Exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). A positive allosteric modulator of rat P2X7.
备注
GW791343 HCl is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
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