2-[(3,4-二氟苯基)氨基]-N-[2-甲基-5-(1-哌嗪基甲基)苯基]乙酰胺盐酸盐

别名：2-[(3,4-二氟苯基)氨基]-N-[2-甲基-5-(1-哌嗪基甲基)苯基]乙酰胺盐酸盐产品编号：276476 CAS号：309712-55-8 分子式：C₂₀H₂₄F₂N₄O·3HCl 分子量：483.81

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订货信息

订货编号	产品名称	规格	包装	价格	数量	操作
A61742-10mg	2-[(3,4-二氟苯基)氨基]-N-[2-甲基-5-(1-哌嗪基甲基)苯基]乙酰胺盐酸盐	≥99.0%	10mg	4397.00

化学性质

属性
溶解性
DMSO mg/mL
Water mg/mL
Ethanol mg/mL
存贮条件
储存温度-20°C
描述
别名
2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride;2-(3,4-difluorophenylamino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide trihydrochloride
生化机理

GW791343 is a P2X7 allosteric modulator. Exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). A positive allosteric modulator of rat P2X7.

备注
GW791343 HCl is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.

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