化学性质
属性
存贮条件
储存温度 2-8°C
描述
产品介绍
L-Amino Acid Oxidase is an oligomeric glycoprotein composed of unequal amounts of two different approximately 70 kDa subunits. Three electrophoretically different isozymes occur as different combinations of the two subunits. there are approximately two moles of FAD per mole of holo-enzyme. L-amino acid oxidase catalyzes the oxidative deamination of a number of L-amino acids. The enzyme is absolutely specific for L-isomers. The Aladdin product is prepared according to Wellner and Meister, JBC, 235, 2013, (1960) to the point just prior to crystallization.
别名
;L-AAO;L-Amino acid;oxygen oxidoreductase(deaminating)
生化机理
L-Amino acid oxidase is a flavoprotein with a molecular weight of 130 kDa. It consists of two different subunits of approximately 70,000 Da. Each molecule of holoenzyme has two FAD molecules. It is a glycoprotein containing about 2-5% carbohydrate, including sialic acid. Optimum pH is approximately 7.5.The enzyme may be reversibly inactivated by incubation in phosphate buffer, pH 7.5 at 38 °C. L-amino acid oxidase is involved in various metabolic pathways such as alanine and aspartate metabolism, methionine metabolism, valine, leucine and isoleucine degradation, tyrosine metabolism, phenylalanine metabolism, tryptophan metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, and alkaloid biosynthesis.It occurs in many snake venoms apart from microorganisms and animal tissue, especially in kidney and liver.
备注
An aqueous solution with toluene added as a preservative.
应用
L-amino acid oxidase (LAAO) is used to convert L-amino acids to their corresponding α-keto acids. L-amino acid oxidase, from Sigma, has been used in leucine aminopeptidase (LAP) activity assays.
-----------------------
储存条件2-8°CformpowdercoloryellowMerck13，414
危险属性
标识符号
GHS06;
信号词
Danger
风险声明 (欧洲)
R26/27/28
安全声明（欧洲）
S36/37/39;S45
警示性声明
P260,P264,P280,P284,P301 P310,P302 P350
危害码（欧洲）
T
危害声明
H300 H310 H330
WGK德国
3
-----------------------
危险品标志 ：T+
危险类别码 ：26/27/28
安全说明 ：36/37/39-45
危险品运输编号 ：UN 3462 6.1/PG 1WGK Germany3
RTECS号 ：RQ8300000F10-18-21HazardClass6.1(b)PackingGroupIII
