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精氨酸-甘氨酸-天冬氨酸-丝氨酸-西亚试剂有售,精氨酸-甘氨酸-天冬氨酸-丝氨酸分子式,精氨酸-甘氨酸-天冬氨酸-丝氨酸价格,西亚试剂有各种化学试剂,生物试剂,分析试剂,材料试剂,高端化学,耗材,实验室试剂,科研试剂,色谱耗材www.xiyashiji.com

精氨酸-甘氨酸-天冬氨酸-丝氨酸

别名:精氨酸-甘氨酸-天冬氨酸-丝氨酸 产品编号:271616 CAS号:91037-65-9 分子式:C15H27N7O8 分子量:433.42

订货信息

订货编号 产品名称 规格 包装 价格 数量 操作
A60628-2mg 精氨酸-甘氨酸-天冬氨酸-丝氨酸 ≥95.0%(HPLC) 2mg 455.00

A60628-5mg 精氨酸-甘氨酸-天冬氨酸-丝氨酸 ≥95.0%(HPLC) 5mg 901.00

A60628-25mg 精氨酸-甘氨酸-天冬氨酸-丝氨酸 ≥95.0%(HPLC) 25mg 2590.00

化学性质


属性
密度
1.6500
存贮条件
储存温度-20°C
描述
产品介绍
Arg-Gly-Asp-Ser.It is a key component of the cell attachment domain of fibronectin. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts (NRKcells) to fibronectin and synthetic fibronectin peptides coupled to protein-coated plastic. Further investigation indicated that the free RGDS peptide inhibited the attachment of NRK cells to fibronectin coated substrates. The RGDS sequence has been shown to occur in several other proteins, such as the λ receptor on E. coli and the Sindbis coat protein. RGDS is also a target sequence for spirochete adherence of the syphilis bacterium Treponema pallidum.It  has been shown to block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. The effect of RGDS on transforming growth factor β1 (TGFβ1) mRNA expression and secretion in cultured human mesangial cells has been investigated. RGDS has been utilized in a study of integrin-mediated signal transduction in cultured cells from the sponge Suberites domuncula. RGDS has been demonstrated to mitigate the binding of Mycobacterium tuberculosis to murine alveolar macrophages.
别名
RGDS;L-精氨酰甘氨酰-L-alpha-天冬氨酰-L-丝氨酸;RGDS;Arginyl-glycyl-aspartyl-serine;H-Arg-Gly-Asp-Ser-OH;Fibronectin Inhibitor;L-Arginylglycyl-L-alpha-aspartyl-L-serine
应用
A tetrapeptide that supports fibroblast attachment and inhibits fibronectin binding.

危险属性


个人防护设备
Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国
3

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