化学性质
属性
存贮条件
储存温度 -20°C
描述
别名
血小板活化因子(C18);C18-02:0 PC;[(2R)-2-Acetoxy-3-Octadecoxy-Propyl] 2-Trimethylammonioethyl Phosphate; [(2R)-2-Acetoxy-3-Octadecoxypropyl] 2-Trimethylammonioethyl Phosphate; [(2R)-2-Acetoxy-3-Stearyloxy-Propyl] 2-Trimethylammonioethyl Phosphate
生化机理
PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the de novo and remodeling pathways. PAF C-18 is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages. PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and PAF C-18 enhances the spreading of plated macrophages. Pathological processes involving PAF include necrotizing enterocolitis, asthma, allergy and inflammation.
应用
A naturally occurring phospholipid involved in inflammation and other physiological processes. -----------------------
储存条件−20°C溶解度chloroform: 10 mg/mL
危险属性
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安全说明 ：24/25WGK Germany3
