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香叶基香叶醇

别名:香叶基香叶醇 产品编号:248975 CAS号:24034-73-9 分子式:C20H34O 分子量:290.48300

订货信息

订货编号 产品名称 规格 包装 价格 数量 操作
A53611-20mg 香叶基香叶醇 ≥95.0% 20mg 416.00

A53611-50mg 香叶基香叶醇 ≥95.0% 50mg 799.00

A53611-100mg 香叶基香叶醇 ≥95.0% 100mg 1576.00

化学性质


属性
溶解性
Soluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), chloroform, dichloromethane, ethyl acetate, hexane, ether, and acetone.
存贮条件
储存温度-20°C,充氩保存
描述
产品介绍
Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. This compound has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro When working with statins, geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. It has been found to induce apoptosis in HL-60 cells.
别名
all trans-3,7,11-15-四甲基-2,6,10,14-十六烷四烯-1-醇;(2E,6E,10E)-3,7,11,15-四甲基-2,6,10,14-十六碳四烯-1-醇
生化机理
As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.
应用
香叶基香叶醇本身具有广泛的生理活性,是多种具有生化意义的产物的生化合成前体,如萜类、胡萝卜素、甾体、胆固醇和紫杉醇等。

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